• Odegrip et al. (2004) PNAS, 101, 2806–2810

• Eldridge et al. (2009) PEDS, 22, 691–698

A faster, better approach

to biologics discovery

Advantages include:

• No need to clone— vast protein library screening without cloning
• Rapid searching of sequence space.
• > 10¹³ Effective library size based on library efficiency of 40%.
• Robust technology with enrichment rates of > 10³ - 10⁵
• Custom libraries, both de novo and maturation, can be assembled in days.
• Isogenica peptide libraries available for screening

CIS display enables the rapid construction of new peptide, polypeptide and antibody libraries and the selection of lead compounds.

The CIS display system employs cycles of enrichment to rapidly search vast libraries of molecules in parallel for the optimal candidate.