LlamdA®
Single domain VHH discovery engine.
Intelligent & Precise
Incorporating intelligent design with the precision of the COLIBRA® library construction system.
LlamdA® is a state-of-the-art, highly diverse, synthetic VHH library which, when combined with the power of CIS display, interrogates more than 1013 library members: equivalent to the circulating repertoire of one million llamas.
LlamdA®offers optimal expression of maximised functional diversity.
State-of-the-Art Technology
The humanised library retains camelid hallmark residues to confer optimised solubility and stability of LlamdA® antibodies.
Purely in vitro, Isogenica’s LlamdA® enables speed and efficiency unmatched by animal immunisation.
Selected Publications
LlamdA®
Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Nature Communications 2019 10 (365)
CIS Display
CIS display: In vitro selection of peptides from libraries of protein-DNA complexes.
COLIBRA®
Codon-Precise, Synthetic, Antibody Fragment Libraries Built Using Automated Hexamer Codon Additions and Validated through Next Gen Sequencing
Antibodies 2015, 4(2), 88-102
