LlamdA®

Single domain VHH discovery engine.

Intelligent & Precise

Incorporating intelligent design with the precision of the COLIBRA® library construction system.

LlamdA® is a state-of-the-art, highly diverse, synthetic VHH library which, when combined with the power of CIS display, interrogates more than 1013 library members: equivalent to the circulating repertoire of one million llamas.

LlamdA®offers optimal expression of maximised functional diversity.

State-of-the-Art Technology

The humanized library retains camelid hallmark residues to confer optimised solubility and stability of LlamdA® antibodies.

Purely in vitro, Isogenica’s LlamdA® enables speed and efficiency unmatched by animal immunisation.

LlamdA Antibody Discovery Engine

Selected Publications

LlamdA®

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.

Nature Communications 2019 10 (365)

CIS Display

CIS display: In vitro selection of peptides from libraries of protein-DNA complexes.

COLIBRA®

Codon-Precise, Synthetic, Antibody Fragment Libraries Built Using Automated Hexamer Codon Additions and Validated through Next Gen Sequencing

Antibodies 2015, 4(2), 88-102